BDBM50028970 6-Amino-5,6,7,8-tetrahydro-naphthalene-1,2-diol::CA inhibitor, 4::CHEMBL163912

SMILES NC1CCc2c(C1)ccc(O)c2O

InChI Key InChIKey=FSMRTTIHBZCVJG-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50028970   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Agri Ibrahim Cecen University

LigandPNGBDBM50028970(6-Amino-5,6,7,8-tetrahydro-naphthalene-1,2-diol | ...)
Affinity DataKi:  380nM ΔG°:  -8.75kcal/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Agri Ibrahim Cecen University

LigandPNGBDBM50028970(6-Amino-5,6,7,8-tetrahydro-naphthalene-1,2-diol | ...)
Affinity DataKi:  970nM ΔG°:  -8.20kcal/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Agri Ibrahim Cecen University

LigandPNGBDBM50028970(6-Amino-5,6,7,8-tetrahydro-naphthalene-1,2-diol | ...)
Affinity DataKi:  4.51E+4nM ΔG°:  -5.92kcal/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Crete

Curated by ChEMBL
LigandPNGBDBM50028970(6-Amino-5,6,7,8-tetrahydro-naphthalene-1,2-diol | ...)
Affinity DataIC50:  700nMAssay Description:Inhibitition of binding of [3H]-spiroperidol to Dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed