BDBM50029417 CHEMBL277363::[4-(4-Methoxy-phenyl)-4H-benzo[b]pyrrolo[1,2-d][1,4]thiazin-1-ylmethyl]-dimethyl-amine
SMILES COc1ccc(cc1)C1Sc2ccccc2-n2c(CN(C)C)ccc12
InChI Key InChIKey=TYMAXGQYKWRKGX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50029417
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]nitrendipine from calcium channel receptorMore data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Calcium antagonistic activity by measuring [3H]-nitrendipine displacement from rat heart L-type [Ca2+] channelMore data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Displacement of [3H]nitrendipine from calcium channel receptorMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena
Curated by ChEMBL
Universita' Degli Studi Di Siena
Curated by ChEMBL
Affinity DataIC50: 0.430nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+3nMAssay Description:Ability to inhibit [3H]-PK 11195 binding to peripheral-type benzodiazepine receptor(PBR) in rat cerebral cortex homogenate.More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Ability to inhibit [3H]nitrendipine binding to the L-type calcium channel receptor(CCR) in rat heart homogenateMore data for this Ligand-Target Pair