BDBM50029515 CHEMBL141584::tert-butyloxy carbonyl-D-Phe-azetidine-2-carboxylate-Arg-H

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

InChI Key InChIKey=PUSXAFWVXFYXRA-BZSNNMDCSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50029515   

TargetSerine protease 1(Bos taurus (bovine))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029515(CHEMBL141584 | tert-butyloxy carbonyl-D-Phe-azetid...)
Affinity DataIC50:  9.70nMAssay Description:In vitro Enzyme Inhibitory activity measured against TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029515(CHEMBL141584 | tert-butyloxy carbonyl-D-Phe-azetid...)
Affinity DataIC50:  900nMAssay Description:In vitro Enzyme Inhibitory activity against t-PA(Tissue plasminogen activator).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029515(CHEMBL141584 | tert-butyloxy carbonyl-D-Phe-azetid...)
Affinity DataIC50:  18nMAssay Description:In vitro Enzyme Inhibitory activity measured against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Bos taurus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029515(CHEMBL141584 | tert-butyloxy carbonyl-D-Phe-azetid...)
Affinity DataIC50:  1.30E+3nMAssay Description:In vitro Enzyme Inhibitory activity measured against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029515(CHEMBL141584 | tert-butyloxy carbonyl-D-Phe-azetid...)
Affinity DataIC50:  360nMAssay Description:In vitro Enzyme Inhibitory activity measured against PlasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed