BDBM50029767 5-{4-chloro-3-[(1E)-3-ethyltriaz-1-enyl]phenyl}-6-ethylpyrimidine-2,4-diamine::CHEMBL357573

SMILES CCN=NNc1cc(ccc1Cl)-c1c(N)nc(N)nc1CC

InChI Key InChIKey=CPYNKCXEGCQNNF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50029767   

TargetDihydrofolate reductase(Pneumocystis carinii)
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50029767(5-{4-chloro-3-[(1E)-3-ethyltriaz-1-enyl]phenyl}-6-...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibitory activity of Pneumocystis carinii growth culture of the compound was determined against dihydrofolate reductase .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50029767(5-{4-chloro-3-[(1E)-3-ethyltriaz-1-enyl]phenyl}-6-...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibitory activity was determined against dihydrofolate reductase in Pneumocystis carinii .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50029767(5-{4-chloro-3-[(1E)-3-ethyltriaz-1-enyl]phenyl}-6-...)
Affinity DataIC50:  1.89E+4nMAssay Description:Inhibitory activity of the compound was determined against dihydrofolate reductase in rat .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed