BDBM50030476 CHEMBL458603
SMILES Clc1ccc(cc1)-c1nc2sccn2c1\C=N\OCc1ccc(Cl)c(Cl)c1
InChI Key InChIKey=ZQWBOKJVVYNKTL-AUEPDCJTSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50030476
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 75nMAssay Description:Agonist activity at human CAR expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 510nMAssay Description:Agonist activity at human CAR3 expressed in African green monkey COS-1 cells cotransfected with RXRalpha after 24 hrs by CYP2B6-luciferase reporter g...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Agonist activity at CAR LBD (108 to 348 residues) expressed in human HepG2 cells assessed as receptor binding to PGC1alpha by lanthascreenTR-FRET coa...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 570nMAssay Description:Agonist activity at human constitutive androstane receptor expressed in HepG2 cells co-expressing CYP2B6 incubated for 23 hrs by One-Glo luciferase r...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 5nMAssay Description:Agonist activity at human CARMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 620nMAssay Description:Agonist activity at human CAR transfected in human HepG2 cells cotransfected with CYP2B6 incubated for 23 hrs by luciferase reported gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 49nMAssay Description:Agonist activity at Polyhistidine-tagged human CAR LBD expressed in Escherichia coli by FRET-based assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 49nMAssay Description:Agonist activity at Polyhistidine-tagged human CAR LBD expressed in Escherichia coli by FRET-based assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataEC50: 990nMAssay Description:Agonist activity at human PXR transfected in human HepG2 cells cotransfected with CYP3A4 incubated for 23 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair