BDBM50030947 CHEMBL331845::N-[2-(6-Amino-purin-9-yl)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-3-yl]-3-methoxy-benzamide

SMILES COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(N)ncnc12

InChI Key InChIKey=ZUKVLQWGVRRKFN-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50030947   

TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030947(CHEMBL331845 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Affinity DataIC50:  300nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Leishmania mexicanaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030947(CHEMBL331845 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Affinity DataIC50:  2.20E+3nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Trypanosoma bruceiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030947(CHEMBL331845 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Affinity DataIC50:  2.20E+6nMAssay Description:Inhibition of glyceraldehyde-3-phosphate dehydrogenase in Trypanosoma bruceiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030947(CHEMBL331845 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Affinity DataIC50:  8.00E+5nMAssay Description:Inhibitory activity measured for Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in Leishmania. mexicanaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030947(CHEMBL331845 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Affinity DataIC50:  3.00E+5nMAssay Description:TInhibition of glyceraldehyde-3-phosphate dehydrogenase in Leishmania mexicanaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030947(CHEMBL331845 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of human erythrocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030947(CHEMBL331845 | N-[2-(6-Amino-purin-9-yl)-4-hydroxy...)
Affinity DataIC50: >1.00E+7nMAssay Description:Inhibition of Glyceraldehyde-3-phosphate dehydrogenase in human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed