BDBM50030949 (2R,3R,4S,5R)-2-(6-Amino-8-thiophen-2-yl-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol::CHEMBL124807

SMILES Nc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(nc12)-c1cccs1

InChI Key InChIKey=LMNBPJQPSDYDKY-GUSNPEKLSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50030949   

TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030949((2R,3R,4S,5R)-2-(6-Amino-8-thiophen-2-yl-purin-9-y...)
Affinity DataKi:  3.00E+5nMAssay Description:Inhibition of Leishmania mexicana GAPDH(glyceraldehyde-3-phosphate dehydrogenase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030949((2R,3R,4S,5R)-2-(6-Amino-8-thiophen-2-yl-purin-9-y...)
Affinity DataIC50:  500nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Leishmania mexicanaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030949((2R,3R,4S,5R)-2-(6-Amino-8-thiophen-2-yl-purin-9-y...)
Affinity DataIC50:  5.00E+5nMAssay Description:TInhibition of glyceraldehyde-3-phosphate dehydrogenase in Leishmania mexicanaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030949((2R,3R,4S,5R)-2-(6-Amino-8-thiophen-2-yl-purin-9-y...)
Affinity DataIC50:  600nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyd 3-phosphate dehydrogenase (gGAPDH) of Trypanosoma bruceiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030949((2R,3R,4S,5R)-2-(6-Amino-8-thiophen-2-yl-purin-9-y...)
Affinity DataIC50:  6.00E+5nMAssay Description:Inhibition of glyceraldehyde-3-phosphate dehydrogenase in Trypanosoma bruceiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030949((2R,3R,4S,5R)-2-(6-Amino-8-thiophen-2-yl-purin-9-y...)
Affinity DataIC50:  1.30E+3nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of human erythrocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030949((2R,3R,4S,5R)-2-(6-Amino-8-thiophen-2-yl-purin-9-y...)
Affinity DataIC50:  1.30E+6nMAssay Description:Inhibition of Glyceraldehyde-3-phosphate dehydrogenase in human erythrocytes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed