BDBM50031338 CHEMBL3358090

SMILES COc1ccc(cc1OCCNS(C)(=O)=O)-c1nc([C@H](C)Sc2nc(N)cc(N)n2)c(C)s1

InChI Key InChIKey=MBPWFMBRNJJXFY-LBPRGKRZSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50031338   

TargetDeoxycytidine kinase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50031338(CHEMBL3358090)
Affinity DataKi:  585nMAssay Description:Apparent inhibition of human dCK by steady-state kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50031338(CHEMBL3358090)
Affinity DataIC50:  605nMAssay Description:Apparent inhibition of human dCK assessed as phosphorylation activity by spectroscopic NADH-dependent enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxycytidine kinase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50031338(CHEMBL3358090)
Affinity DataIC50:  94nMAssay Description:Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of [3H]-dC uptake by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed