BDBM50032732 CHEMBL3354708
SMILES COc1cncc(c1)-c1ccc2Oc3ccc(OCC(C)(C)C)cc3[C@]3(COC(N)=N3)c2c1
InChI Key InChIKey=ZTVRKPQAQQUAMM-SANMLTNESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50032732
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human ERG expressing HEK293 cells by [3H]dofetilide binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of BACE1 in HEK293T cells expressing APPswedish mutant assessed as inhibition of amyloid beta 40 production by sandwich ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as enhancement of fluorescence intensityMore data for this Ligand-Target Pair