BDBM50036377 (Z)-6-{2-[1-(4-Fluoro-phenoxy)-1-methyl-ethyl]-4-pyridin-3-yl-[1,3]dioxan-5-yl}-hex-4-enoic acid::CHEMBL163278

SMILES CC(C)(Oc1ccc(F)cc1)C1OCC(C\C=C/CCC(O)=O)C(O1)c1cccnc1

InChI Key InChIKey=GIBSMNWSGDDKDB-ARJAWSKDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036377   

TargetProstacyclin synthase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036377((Z)-6-{2-[1-(4-Fluoro-phenoxy)-1-methyl-ethyl]-4-p...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036377((Z)-6-{2-[1-(4-Fluoro-phenoxy)-1-methyl-ethyl]-4-p...)
Affinity DataIC50:  51nMAssay Description:In vitro Inhibition of thromboxane synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed