BDBM50038370 2-(2,5-Dimethoxy-4-trifluoromethyl-phenyl)-1-methyl-ethylamine::CHEMBL6620::Racemic DOTFM
SMILES COc1cc(c(OC)cc1CC(C)N)C(F)(F)F
InChI Key InChIKey=WPGOTSORDNBMHP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50038370
Affinity DataKi: 2.20nMAssay Description:Binding affinity at cloned rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.78nMAssay Description:Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in Sprague-Dawley rat brain by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
Affinity DataKi: 2.23E+3nMAssay Description:Tested for the binding affinity against the site labelled by the 5-hydroxytryptamine 1A receptor agonist [3H]- 8-OH-DPATMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Universidad De Chile
Curated by ChEMBL
Universidad De Chile
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspensionMore data for this Ligand-Target Pair
Affinity DataEC50: 68.4nMAssay Description:Ability to stimulate phosphoinositide hydrolysis in NIH3T3 cells expressing the 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair