BDBM50039252 1-{2-[(3-Fluoro-4-methoxy-phenyl)-(3-fluoro-phenyl)-phenyl-methoxy]-ethyl}-piperidine-3-carboxylic acid::CHEMBL74138

SMILES COc1ccc(cc1F)C(OCCN1CCCC(C1)C(O)=O)(c1ccccc1)c1cccc(F)c1

InChI Key InChIKey=QPLCEYNIPVOVMI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50039252   

TargetSodium- and chloride-dependent GABA transporter 3(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039252(1-{2-[(3-Fluoro-4-methoxy-phenyl)-(3-fluoro-phenyl...)
Affinity DataIC50:  1.98E+5nMAssay Description:Inhibitory activity against human sodium and chloride dependent GABA transporter 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Rattus norvegicus)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039252(1-{2-[(3-Fluoro-4-methoxy-phenyl)-(3-fluoro-phenyl...)
Affinity DataIC50:  4.17E+5nMAssay Description:Inhibitory activity against rat GABA transporter-2 (rGAT2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039252(1-{2-[(3-Fluoro-4-methoxy-phenyl)-(3-fluoro-phenyl...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed