BDBM50039731 3-(2-(1-benzylpiperidin-4-yl)ethyl)benzo[d]isoxazol-6-ol::3-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-benzo[d]isoxazol-6-ol::CHEMBL92463

SMILES Oc1ccc2c(CCC3CCN(Cc4ccccc4)CC3)noc2c1

InChI Key InChIKey=PPMPPMKWHZDSNI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50039731   

TargetAcetylcholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50039731(3-(2-(1-benzylpiperidin-4-yl)ethyl)benzo[d]isoxazo...)
Affinity DataIC50:  25.7nMAssay Description:Inhibition of human acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50039731(3-(2-(1-benzylpiperidin-4-yl)ethyl)benzo[d]isoxazo...)
Affinity DataIC50:  26nMAssay Description:Evaluated for the in vitro inhibition of the Acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50039731(3-(2-(1-benzylpiperidin-4-yl)ethyl)benzo[d]isoxazo...)
Affinity DataIC50:  26nMAssay Description:Inhibition against Acetylcholinesterase (AChE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50039731(3-(2-(1-benzylpiperidin-4-yl)ethyl)benzo[d]isoxazo...)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity against Acetylcholinesterase enzyme using human AChE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50039731(3-(2-(1-benzylpiperidin-4-yl)ethyl)benzo[d]isoxazo...)
Affinity DataIC50:  26nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed