BDBM50041296 1-(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl)-propan-1-one::CHEMBL23142::PTT(-)

SMILES CCC(=O)C1C2CCC(CC1c1ccc(C)cc1)N2C

InChI Key InChIKey=PZEAJTAVRYLBTK-UHFFFAOYSA-N

Data  9 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50041296   

TargetTransporter(Rattus norvegicus)
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50041296(1-(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl...)
Affinity DataKi:  65nMAssay Description:Affinity for the displacement of [3H]-paroxetine binding to norepinephrine transporter (NET) in rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50041296(1-(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl...)
Affinity DataKi:  131nMAssay Description:Affinity for the displacement of [3H]-paroxetine binding to serotonin transporter (SERT) in rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
State University Of New York

Curated by ChEMBL
LigandPNGBDBM50041296(1-(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl...)
Affinity DataIC50:  8.20nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed