BDBM50041933 5-Methyl-6-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-thieno[2,3-d]pyrimidine-2,4-diamine::CHEMBL322861

SMILES COc1cc(CCc2sc3nc(N)nc(N)c3c2C)cc(OC)c1OC

InChI Key InChIKey=WRLXLJUKEGXYMH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50041933   

TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041933(5-Methyl-6-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-thi...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041933(5-Methyl-6-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-thi...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041933(5-Methyl-6-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-thi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041933(5-Methyl-6-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-thi...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of dihydrofolate reductase in Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed