BDBM50041961 ((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(+)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(1S,2R)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::CHEMBL278751::UH-232

SMILES CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C

InChI Key InChIKey=BTOJYCTUJJHANF-WMLDXEAASA-N

Data  19 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50041961   

TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  4nMAssay Description:Binding towards Dopamine receptor D3 expressed in CHO-K1 cells using [3H]spiperone More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity of the compound was measured at cloned mammalian dopamine D3 receptor expressed in CHO-K1 cells (using [3H]- spiperone)More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  4.20nMAssay Description:Tested in vitro for the inhibition of [3H]-U-86,170 binding to Dopamine receptor D3, expressed in cloned CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  13nMAssay Description:Binding affinity against human Dopamine receptor D3 in Chinese hamster ovary cells using [3H]spiperone.More data for this Ligand-Target Pair
In DepthDetails
TargetD(2) dopamine receptor(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  13nMAssay Description:Compound was tested for agonistic activity against D2 receptor from cloned CHO cells, used [3H]U-86170 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
University Of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  13nMAssay Description:Binding affinity for sigma receptor using 2 nM of [3H]-DTG as radioligand, in membranes from brain minus cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  15nMAssay Description:Tested in vitro for the inhibition of [3H]-raclopride binding to Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  15nMAssay Description:Binding affinity of the compound was measured at cloned mammalian dopamine D2 receptor expressed in CHO-K1 cells (using [3H]-U-86,170)More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(BOVINE)
University Of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  18nMAssay Description:Evaluated for binding towards Dopamine receptor D2 using [3H]-spiperone as radioligand, in cloned mammalian receptors expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  22nMAssay Description:Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  48nMAssay Description:Tested in vitro for the inhibition of [3H]-spiperone binding to Dopamine receptor D4, expressed in cloned CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  48nMAssay Description:Binding affinity of the compound was measured at cloned mammalian dopamine D4 receptor expressed in CHO-K1 cells (using [3H]- spiperone)More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  48nMAssay Description:Binding towards dopamine receptor D4 expressed in CHO-K1 cells using [3H]spiperone More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  63nMAssay Description:Binding affinity against human Dopamine receptor D2 in mouse LtK- cells using [3H]spiperone.More data for this Ligand-Target Pair
In DepthDetails
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  70nMAssay Description:Binding towards Dopamine receptor D3 expressed in CHO-K1 cells using [3H]spiperone More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  100nMAssay Description:Evaluated for binding towards Dopamine receptor D2 using [3H]-N-0437 as radioligand from rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  168nMAssay Description:Tested in vitro for the inhibition of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor, expressed in cloned CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  168nMAssay Description:Binding affinity of the compound was measured at cloned mammalian 5-HT1A receptor expressed in CHO-K1 cells (using [3H]-8-OH-DPAT )More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50041961(((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...)
Affinity DataKi:  228nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor from bovine hippocampus, used [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed