BDBM50042406 3-[4-Methyl-2-(3-phenyl-propionylamino)-pentanoylamino]-2-oxo-pentanoic acid ethyl ester::CHEMBL117801

SMILES CCOC(=O)C(=O)C(CC)NC(=O)C(CC(C)C)NC(=O)CCc1ccccc1

InChI Key InChIKey=YQQXZFGMNDTHMS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50042406   

TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042406(3-[4-Methyl-2-(3-phenyl-propionylamino)-pentanoyla...)
Affinity DataKi:  1.20E+3nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042406(3-[4-Methyl-2-(3-phenyl-propionylamino)-pentanoyla...)
Affinity DataKi:  2.30E+4nMpH: 5.2Assay Description:Inhibition of alpha-keto esters towards cathepsin B at pH 5.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042406(3-[4-Methyl-2-(3-phenyl-propionylamino)-pentanoyla...)
Affinity DataKi:  4.00E+4nMAssay Description:Inhibitory activity of alpha-keto esters towards calpain 1 at pH 8.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed