BDBM50042409 3-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamino)-2-oxo-pentanoic acid butyl ester::CHEMBL333388

SMILES CCCCOC(=O)C(=O)C(CC)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1

InChI Key InChIKey=YBCYKWLFCIPEMH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50042409   

TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042409(3-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamin...)
Affinity DataKi:  400nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042409(3-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamin...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibitory activity of alpha-keto esters towards calpain 1 at pH 8.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042409(3-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamin...)
Affinity DataKi:  4.00E+3nMpH: 5.2Assay Description:Inhibition of alpha-keto esters towards cathepsin B at pH 5.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042409(3-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamin...)
Affinity DataKi:  1.00E+4nMpH: 6.0Assay Description:Inhibitory activity of alpha-ketoesters towards papain at pH 6.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed