BDBM50042426 3-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamino)-2-oxo-4-phenyl-butyric acid butyl ester::CHEMBL117450

SMILES CCCCOC(=O)C(=O)C(Cc1ccccc1)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1

InChI Key InChIKey=DWAGOXRYPXDHHS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50042426   

TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042426(3-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamin...)
Affinity DataKi:  1.10E+3nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042426(3-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamin...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibitory activity of alpha-keto esters towards calpain 1 at pH 8.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042426(3-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamin...)
Affinity DataKi:  1.50E+4nMpH: 5.2Assay Description:Inhibition of alpha-keto esters towards cathepsin B at pH 5.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042426(3-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamin...)
Affinity DataKi:  1.50E+4nMpH: 6.0Assay Description:Inhibitory activity of alpha-ketoesters towards papain at pH 6.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed