BDBM50042992 3-(4-Hydroxy-3-methoxy-phenyl)-1-(4-methoxy-phenyl)-propenone::CHEMBL130639

SMILES COc1ccc(cc1)C(=O)\C=C\c1ccc(O)c(OC)c1

InChI Key InChIKey=HOYSEOCCEVHZSJ-YCRREMRBSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50042992   

TargetStromal cell-derived factor 1(Homo sapiens (Human))
Umr7200 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50042992(3-(4-Hydroxy-3-methoxy-phenyl)-1-(4-methoxy-phenyl...)
Affinity DataKi:  1.78E+3nMAssay Description:Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50042992(3-(4-Hydroxy-3-methoxy-phenyl)-1-(4-methoxy-phenyl...)
Affinity DataIC50:  1.20E+4nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50042992(3-(4-Hydroxy-3-methoxy-phenyl)-1-(4-methoxy-phenyl...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article