BDBM50043643 CHEMBL3355528

SMILES CN1CCc2ccc(Nc3ncc4c(n3)n3ccnc3n(-c3ccccc3Cl)c4=O)cc2C1

InChI Key InChIKey=PFAIKAPJSZVPTC-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043643   

TargetWee1-like protein kinase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50043643(CHEMBL3355528)
Affinity DataKi:  1.60nMAssay Description:Inhibition of GST-tagged human Wee1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50043643(CHEMBL3355528)
Affinity DataEC50:  220nMAssay Description:Inhibition of human Weel1 in human NCI-H1299 cells assessed as phosphorylation of Cdk1 after overnight incubation by ELISA PD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed