BDBM50043679 6-[3-Fluoro-5-(4-hydroxy-tetrahydro-pyran-4-yl)-phenoxymethyl]-1-methyl-1H-quinolin-2-one::CHEMBL21841

SMILES Cn1c2ccc(COc3cc(F)cc(c3)C3(O)CCOCC3)cc2ccc1=O

InChI Key InChIKey=ZLIRHRGDDUHGHJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50043679   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50043679(6-[3-Fluoro-5-(4-hydroxy-tetrahydro-pyran-4-yl)-ph...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed