BDBM50044246 CHEMBL3314042

SMILES [H][C@@]12C[C@]1([H])C[C@@H](C2)Oc1cc(ccc1N(C)C(=O)c1c(F)cccc1Cl)-c1cc(ccc1Cl)C(N)=O

InChI Key InChIKey=DUIXDTSBHJPLIP-PIIMJCKOSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044246   

TargetNuclear receptor ROR-gamma(Mus musculus)
Genentech

Curated by ChEMBL
LigandPNGBDBM50044246(CHEMBL3314042)
Affinity DataEC50: <100nMAssay Description:Activity at RoRc in mouse CD4+ T cells assessed as inhibition of IL-17 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50044246(CHEMBL3314042)
Affinity DataEC50: <100nMAssay Description:Inverse agonist activity at human RoRc-LBD expressed in cells assessed as TRAP-220 coactivator peptide recruitmentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed