BDBM50044784 CHEBI:79090::SB-202190::US10865384, Compound SB202190

SMILES Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1

InChI Key InChIKey=QHKYPYXTTXKZST-UHFFFAOYSA-N

Data  33 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044784   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50044784(CHEBI:79090 | SB-202190 | US10865384, Compound SB2...)
Affinity DataKd:  3.40E+3nMAssay Description:Binding affinity to recombinant human His6-TEV protease-tagged BRD4 bromodomain 1 expressed in bacteria by isothermal titration calorimetric methodMore data for this Ligand-Target Pair
TargetBromodomain testis-specific protein(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50044784(CHEBI:79090 | SB-202190 | US10865384, Compound SB2...)
Affinity DataKd:  3.42E+3nMAssay Description:Binding affinity to human N-terminal His6-tagged BRDTexpressed in Escherichia coli BL21 (DE3) cells (21 to 137 residues) incubated for 1 hrMore data for this Ligand-Target Pair
In DepthDetails PubMed