BDBM50049395 5,7,4'-Trihydroxy-6-methoxyflavone::5,7-Dihydroxy-2-(4-hydroxy-phenyl)-6-methoxy-chromen-4-one::5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one::6-methoxy apigenin::6-methoxyapigenin::CHEMBL293776::Hispidulin::NSC-122415::TCMDC-123942::cid_5281628::dinatin
SMILES COc1c(O)cc2oc(cc(=O)c2c1O)-c1ccc(O)cc1
InChI Key InChIKey=IHFBPDAQLQOCBX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 23 hits for monomerid = 50049395
Affinity DataKi: 1.61E+3nMAssay Description:Displacement of specific [3H]-PIA binding from adenosine A1 receptor in rat brain membranes.More data for this Ligand-Target Pair
Affinity DataKi: 1.62E+3nMAssay Description:Ability to displace [3H]N6-phenylisopropyladenosine binding from adenosine A1 receptor.Checked by AuthorMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National Institute Of Diabetes
Curated by ChEMBL
National Institute Of Diabetes
Curated by ChEMBL
Affinity DataKi: 6.48E+3nMAssay Description:Affinity at Adenosine A2A receptor in rat striatal membranes by [3H]- CGS 21680 displacement.More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National Institute Of Diabetes
Curated by ChEMBL
National Institute Of Diabetes
Curated by ChEMBL
Affinity DataKi: 7.59E+3nMAssay Description:Ability to displace [3H]-CGS- 21680 binding from adenosine A2A receptor.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.91E+4nMAssay Description:Inhibition of rat fetal brain CDK5 assessed as phosphorylated histone H1 levels by immuno-precipitationMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Mus musculus)
Institute Of Chinese Materia Medica
Curated by ChEMBL
Institute Of Chinese Materia Medica
Curated by ChEMBL
Affinity DataEC50: 7.30E+3nMAssay Description:Agonist activity at mouse PPARgamma expressed in HEK293 cells co-expressing with Gal4 reporter vector after 24 hrs by dual-luciferase reporter assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Taiwan Academia Sinica
Curated by ChEMBL
Taiwan Academia Sinica
Curated by ChEMBL
Affinity DataIC50: 2.71E+3nMAssay Description:Inhibition of recombinant His6-tagged Pim-1 (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Inhibition of porcine DPP4 after 30 mins by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of Influenza A Jinan/15/90 H3N2 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of Influenza A Jiangsu/10/2003 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.63E+4nMAssay Description:Inhibition of Influenza A PR/8/34 H1N1 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
Universidad De Buenos Aires
Curated by ChEMBL
Universidad De Buenos Aires
Curated by ChEMBL
Affinity DataIC50: 4.66E+4nMAssay Description:Inhibition of Influenza A PR/8/34 H1N1 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
TargetNeuraminidase(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
Universidad De Buenos Aires
Curated by ChEMBL
Universidad De Buenos Aires
Curated by ChEMBL
Affinity DataIC50: 4.62E+4nMAssay Description:Inhibition of Influenza A PR/8/34 H1N1 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Taiwan Academia Sinica
Curated by ChEMBL
Taiwan Academia Sinica
Curated by ChEMBL
Affinity DataIC50: 2.71E+3nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) expressed in Escherichia coli after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)
Curated by ChEMBL
The Chinese University Of Hong Kong (Shenzhen)
Curated by ChEMBL
Affinity DataIC50: 252nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length MNK2 expressed in baculovirus expression system incubated for 1 hr by Kinase Tracer...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)
Curated by ChEMBL
The Chinese University Of Hong Kong (Shenzhen)
Curated by ChEMBL
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of GST-tagged recombinant human full length MNK1 expressed in insect cellsMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)
Curated by ChEMBL
The Chinese University Of Hong Kong (Shenzhen)
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant N-terminal GST/His6-tagged human FLT3 ITD mutant (571 to 993 residues) expressed in Sf9 insect cells incubated for 1 hr by ...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)
Curated by ChEMBL
The Chinese University Of Hong Kong (Shenzhen)
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant His-tagged human FLT3 D835Y mutant (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substra...More data for this Ligand-Target Pair
TargetSteroidogenic factor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
TargetNuclear receptor subfamily 0 group B member 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)
Curated by ChEMBL
The Chinese University Of Hong Kong (Shenzhen)
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substrate incubated ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard Karls University of Tuebingen
Eberhard Karls University of Tuebingen
Affinity DataIC50: 1.86E+4nMT: 2°CAssay Description:The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Eberhard Karls University of Tuebingen
Eberhard Karls University of Tuebingen
Affinity DataIC50: 3.48E+4nMT: 2°CAssay Description:The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n...More data for this Ligand-Target Pair