BDBM50049425 CHEMBL3356083
SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(N)=O
InChI Key InChIKey=WBWUFPXBZXKQCJ-AQJXLSMYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50049425
TargetNeuromedin-U receptor 2(Mus musculus)
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 3nMAssay Description:Agonist activity at mouse NMUR2 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.780nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.590nMAssay Description:Agonist activity at mouse NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.540nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 2(Mus musculus)
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 0.180nMAssay Description:Agonist activity at mouse NMUR2 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.400nMAssay Description:Agonist activity at human NMUR2 expressed in CHO cells assessed as induction of Ca2+ flux measured for 180 secs by Fluo 4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.450nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLI...More data for this Ligand-Target Pair
TargetNeuromedin-U receptor 2(Mus musculus)
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 0.430nMAssay Description:Agonist activity at mouse NMUR2 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLI...More data for this Ligand-Target Pair
Affinity DataEC50: 0.810nMAssay Description:Agonist activity at mouse NMUR1 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLI...More data for this Ligand-Target Pair
Affinity DataEC50: 0.430nMAssay Description:Agonist activity at human NMUR2 expressed in CHO cells assessed as increase in intracellular calcium influx after 180 secs by Fluo 4-AM dye based FLI...More data for this Ligand-Target Pair
Affinity DataIC50: 0.780nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 39nMAssay Description:Agonist activity at human NMUR1 expressed in HEK293 cells assessed as IP3 accumulation after 60 mins in presence of myo-[2-3H(N)]inositol by scintill...More data for this Ligand-Target Pair
Affinity DataEC50: 31nMAssay Description:Agonist activity at human NMUR2 expressed in HEK293 cells assessed as IP3 accumulation after 60 mins in presence of myo-[2-3H(N)]inositol by scintill...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR2 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 31nMAssay Description:Agonist activity at human NMUR2 expressed in HEK293 cells assessed as induction of IP3 levels using myo-[2-3H(N)]-inositol after 60 mins by SPA-based...More data for this Ligand-Target Pair
Affinity DataEC50: 39nMAssay Description:Agonist activity at human NMUR1 expressed in HEK293 cells assessed as induction of IP3 levels using myo-[2-3H(N)]-inositol after 60 mins by SPA-based...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of [3H]-NMU-8 from human NMUR2 expressed in HEK293 cell membranes after 3 hrs by microscintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 9.5nMAssay Description:Agonist activity at mouse NMUR1 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair