BDBM50052090 6,7-Dimethoxy-9-(3,4,5-trimethoxy-phenyl)-3H-naphtho[2,3-c]furan-1-one::CHEMBL284006

SMILES COc1cc(cc(OC)c1OC)-c1c2C(=O)OCc2cc2cc(OC)c(OC)cc12

InChI Key InChIKey=VFULRIWYLLHLAZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50052090   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tan£Be Seiyaku

Curated by ChEMBL
LigandPNGBDBM50052090(6,7-Dimethoxy-9-(3,4,5-trimethoxy-phenyl)-3H-napht...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition in vitro of Phosphodiesterase 5 isolated from guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50052090(6,7-Dimethoxy-9-(3,4,5-trimethoxy-phenyl)-3H-napht...)
Affinity DataIC50:  320nMAssay Description:Inhibitory activity against phosphodiesterase 3 (PDE 3) isolated from cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50052090(6,7-Dimethoxy-9-(3,4,5-trimethoxy-phenyl)-3H-napht...)
Affinity DataIC50:  820nMAssay Description:Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50052090(6,7-Dimethoxy-9-(3,4,5-trimethoxy-phenyl)-3H-napht...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed