BDBM50054333 8-[4-((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL139089

SMILES Fc1cccc2C[C@@H](CCc12)NCCCCN1C(=O)CC2(CCCC2)CC1=O

InChI Key InChIKey=GVWRDZDVMQQZBK-GOSISDBHSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054333   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50054333(8-[4-((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2...)
Affinity DataKi:  4.94nMAssay Description:Displacement of [3H]-raclopride from Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50054333(8-[4-((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2...)
Affinity DataKi:  6.46nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50054333(8-[4-((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]-quinpirole from Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50054333(8-[4-((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2...)
Affinity DataKi:  68nMAssay Description:Inhibition of [3H]-raclopride binding to Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed