BDBM50056230 6-[2-(3,4-Dimethoxy-phenyl)-ethyl]-5,6,7,8-tetrahydro-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL145691

SMILES COc1ccc(CCC2CNc3nc(N)nc(N)c3C2)cc1OC

InChI Key InChIKey=CJJAMOWGVJUCTF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50056230   

TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056230(6-[2-(3,4-Dimethoxy-phenyl)-ethyl]-5,6,7,8-tetrahy...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Pneumocystis carinii (pc)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056230(6-[2-(3,4-Dimethoxy-phenyl)-ethyl]-5,6,7,8-tetrahy...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Rat liver (rl)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056230(6-[2-(3,4-Dimethoxy-phenyl)-ethyl]-5,6,7,8-tetrahy...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Toxoplasma gondii (tg)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed