BDBM50056234 6-[2-(4-Methoxy-phenyl)-ethyl]-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL145528

SMILES COc1ccc(CCc2cnc3nc(N)nc(N)c3c2)cc1

InChI Key InChIKey=SJUSTHFZNREMSJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50056234   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056234(6-[2-(4-Methoxy-phenyl)-ethyl]-pyrido[2,3-d]pyrimi...)
Affinity DataIC50:  250nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Toxoplasma gondii (tg)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056234(6-[2-(4-Methoxy-phenyl)-ethyl]-pyrido[2,3-d]pyrimi...)
Affinity DataIC50:  290nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Pneumocystis carinii (pc)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056234(6-[2-(4-Methoxy-phenyl)-ethyl]-pyrido[2,3-d]pyrimi...)
Affinity DataIC50:  260nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056234(6-[2-(4-Methoxy-phenyl)-ethyl]-pyrido[2,3-d]pyrimi...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056234(6-[2-(4-Methoxy-phenyl)-ethyl]-pyrido[2,3-d]pyrimi...)
Affinity DataIC50:  290nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056234(6-[2-(4-Methoxy-phenyl)-ethyl]-pyrido[2,3-d]pyrimi...)
Affinity DataIC50:  260nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Rat liver (rl)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed