BDBM50057571 4-(5-Cyclohex-1-enyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide::CHEMBL30091

SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(cc1C1=CCCCC1)C(F)(F)F

InChI Key InChIKey=KNNHMHHUEHQWNA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50057571   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50057571(4-(5-Cyclohex-1-enyl-3-trifluoromethyl-pyrazol-1-y...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50057571(4-(5-Cyclohex-1-enyl-3-trifluoromethyl-pyrazol-1-y...)
Affinity DataIC50:  84nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057571(4-(5-Cyclohex-1-enyl-3-trifluoromethyl-pyrazol-1-y...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057571(4-(5-Cyclohex-1-enyl-3-trifluoromethyl-pyrazol-1-y...)
Affinity DataIC50:  83.2nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50057571(4-(5-Cyclohex-1-enyl-3-trifluoromethyl-pyrazol-1-y...)
Affinity DataIC50:  83.2nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed