BDBM50057582 4-[5-(7-Methyl-benzo[1,3]dioxol-5-yl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide::CHEMBL29403

SMILES Cc1cc(cc2OCOc12)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=DKYUBWWDQMKPOP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057582   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50057582(4-[5-(7-Methyl-benzo[1,3]dioxol-5-yl)-3-trifluorom...)
Affinity DataIC50:  6.74E+5nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50057582(4-[5-(7-Methyl-benzo[1,3]dioxol-5-yl)-3-trifluorom...)
Affinity DataIC50:  52.5nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50057582(4-[5-(7-Methyl-benzo[1,3]dioxol-5-yl)-3-trifluorom...)
Affinity DataIC50:  52nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed