BDBM50058391 (S)-1-[(S)-2-(4-Methoxy-benzoylamino)-3-methyl-butyryl]-pyrrolidine-2-carboxylic acid ((S)-3,3,3-trifluoro-1-isopropyl-2-oxo-propyl)-amide::CHEMBL55210
SMILES COc1ccc(cc1)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)C(F)(F)F
InChI Key InChIKey=PNILZVBINXNWHW-FHWLQOOXSA-N
Data 11 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50058391
Affinity DataKi: 1.90nMAssay Description:Inhibitory activity against Human Neutrophil Elastase using acute lung injury model (ALIM) assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:In vitro inhibition constant (Ki) against human leukocyte elastase (HLE-catalyzed hydrolysis of MeO-Suc-Ala-Ala-Pro-Ala-pNA)More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibitory activity against Human Neutrophil Elastase using acute lung injury model (ALIM) assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Binding affinity against human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:In vitro inhibitory activity against human leukocyte elastase was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Binding affinity for human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Binding affinity for human leukocyte elastaseMore data for this Ligand-Target Pair
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Zeneca Pharmaceuticals
Curated by ChEMBL
Zeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Binding affinity of the compound for porcine Pancreatic elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Binding affinity of the compound for human leukocyte cathepsin GMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+4nMAssay Description:Binding affinity of the compound for carboxypeptidase AMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+5nMAssay Description:Binding affinity of the compound for human pancreatic ChymotrypsinogenMore data for this Ligand-Target Pair