BDBM50058993 3-(2-Chloro-benzenesulfonyl)-1-phenyl-imidazolidine-2,4-dione::CHEMBL412452

SMILES Clc1ccccc1S(=O)(=O)N1C(=O)CN(C1=O)c1ccccc1

InChI Key InChIKey=KLSFVSXDHLKRFT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058993   

TargetChymase(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058993(3-(2-Chloro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against human heart chymase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058993(3-(2-Chloro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory activity against human neutrophil cathepsin G.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Suntory

Curated by ChEMBL
LigandPNGBDBM50058993(3-(2-Chloro-benzenesulfonyl)-1-phenyl-imidazolidin...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed