BDBM50059201 CHEMBL3393329

SMILES FC1(F)CCN(C1)c1cc(cc(Nc2cc(ccn2)C#N)n1)C1CCOCC1

InChI Key InChIKey=HINMBDRVCLOXLD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059201   

TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50059201(CHEMBL3393329)
Affinity DataKi:  0.900nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50059201(CHEMBL3393329)
Affinity DataIC50:  70nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed