BDBM50060704 (S)-1-(2-5H-Dibenzo[a,d]cyclohepten-5-yl-acetyl)-pyrrolidine-2-carboxylic acid (4-amino-cyclohexylmethyl)-amide; hydrochloride::CHEMBL555753

SMILES NC1CCC(CNC(=O)[C@@H]2CCCN2C(=O)CC2c3ccccc3C=Cc3ccccc23)CC1

InChI Key InChIKey=HBBDFTMFTGYXBM-ONHYFPECSA-N

Data  6 KI  1 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50060704   

TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060704((S)-1-(2-5H-Dibenzo[a,d]cyclohepten-5-yl-acetyl)-p...)
Affinity DataKi:  3nM Koff:  1.80E+3s-1Assay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060704((S)-1-(2-5H-Dibenzo[a,d]cyclohepten-5-yl-acetyl)-p...)
Affinity DataKi:  1.60E+3nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060704((S)-1-(2-5H-Dibenzo[a,d]cyclohepten-5-yl-acetyl)-p...)
Affinity DataKi:  2.68E+5nMAssay Description:Inhibitory activity against serine protease TPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060704((S)-1-(2-5H-Dibenzo[a,d]cyclohepten-5-yl-acetyl)-p...)
Affinity DataKi:  4.14E+5nMAssay Description:Inhibitory activity against serine protease plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060704((S)-1-(2-5H-Dibenzo[a,d]cyclohepten-5-yl-acetyl)-p...)
Affinity DataKi:  7.75E+5nMAssay Description:Inhibitory activity against serine protease plasma kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060704((S)-1-(2-5H-Dibenzo[a,d]cyclohepten-5-yl-acetyl)-p...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory activity against serine protease Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed