BDBM50060764 CHEMBL3394740::US9458172, 45
SMILES CC(C)n1cc(cn1)S(=O)(=O)c1ccc(CNC(=O)c2cc3ccncc3s2)nc1
InChI Key InChIKey=KUXPZTAQCRKPDT-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50060764
Affinity DataIC50: 7nMAssay Description:Inhibition of human C-terminal His6-tagged NAMPT expressed in Escherichia coli Rosetta(DE3) incubated for 15 mins prior to substrate addition measure...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMpH: 7.5Assay Description:The NAMPT Enzymatic Reaction. The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) i...More data for this Ligand-Target Pair