BDBM50060874 1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione::1:6:8:10:11:13-hexahydroxy-3:4-dimethyl-meso-naphthodianthrene-7:14-dione::CHEMBL286494::Hypericin::Hyperizin::hipericina::hypericine::hypericum red
SMILES Cc1cc(O)c2c3c1c1c(C)cc(O)c4c1c1c3c3c(c(O)cc(O)c3c2=O)c2c(O)cc(O)c(c12)c4=O
InChI Key InChIKey=BTXNYTINYBABQR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50060874
TargetD(3) dopamine receptor(Homo sapiens (Human))
Westfalische Wilhelms-Universitat
Curated by ChEMBL
Westfalische Wilhelms-Universitat
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Binding affinity to dopamine D3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of ATG4B (unknown origin) using proLC3B as substrate by FRET-LC3 assayMore data for this Ligand-Target Pair
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Westfalische Wilhelms-Universitat
Curated by ChEMBL
Westfalische Wilhelms-Universitat
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of CRF1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.98E+5nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.67E+3nMAssay Description:Inhibition of yeast glutathione reductase by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of Atg4B (unknown origin) using YFP-LC3B-EmGFP as substrate after 40 mins by FRET-based assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Westfalische Wilhelms-Universitat
Curated by ChEMBL
Westfalische Wilhelms-Universitat
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP formationMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of Dopamine beta-hydroxylase (unknown origin) incubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human alpha-synuclein filament formation expressed in Escherichia coli BL21(DE3) cells incubated for 72 hrs by thioflavin S based fluor...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
Affinity DataIC50: 1.98E+5nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair