BDBM50060978 3',5'-Bis-trifluoromethyl-biphenyl-4-carboxylic acid::CHEMBL110563

SMILES OC(=O)c1ccc(cc1)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=HIXMMDMXBCYZQQ-UHFFFAOYSA-N

Data  1 Kd  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50060978   

TargetRegulatory protein E2(Human papillomavirus type 16)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060978(3',5'-Bis-trifluoromethyl-biphenyl-4-carboxylic ac...)
Affinity DataKd: >1.00E+7nMAssay Description:Dissociation constant after binding to human papillomavirus E2 DNA-binding domain (DBD) by observing the changes in [15N]-HSQC spectra.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50060978(3',5'-Bis-trifluoromethyl-biphenyl-4-carboxylic ac...)
Affinity DataEC50:  3.70E+3nMAssay Description:Agonist activity at Gal4-LBD fused RXRbeta (unknown origin) expressed in HEK293T cells after 14 to 16 hrs by dual-Glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-gamma(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50060978(3',5'-Bis-trifluoromethyl-biphenyl-4-carboxylic ac...)
Affinity DataEC50:  1.25E+4nMAssay Description:Agonist activity at Gal4-LBD fused RXRgamma (unknown origin) expressed in HEK293T cells after 14 to 16 hrs by dual-Glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50060978(3',5'-Bis-trifluoromethyl-biphenyl-4-carboxylic ac...)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity at Gal4-LBD fused RXRalpha (unknown origin) expressed in HEK293T cells after 14 to 16 hrs by dual-Glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed