BDBM50061879 8-Benzyl-3-[2,2-bis-(4-fluoro-phenyl)-ethyl]-8-aza-bicyclo[3.2.1]octane::8-Benzyl-3-[bis-(4-fluoro-phenyl)-methoxy]-8-aza-bicyclo[3.2.1]octane::CHEMBL12375

SMILES Fc1ccc(cc1)C(OC1CC2CCC(C1)N2Cc1ccccc1)c1ccc(F)cc1

InChI Key InChIKey=YDSZXMRCXLHXST-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50061879   

TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50061879(8-Benzyl-3-[2,2-bis-(4-fluoro-phenyl)-ethyl]-8-aza...)
Affinity DataKi:  63.3nMAssay Description:Binding affinity at dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061879(8-Benzyl-3-[2,2-bis-(4-fluoro-phenyl)-ethyl]-8-aza...)
Affinity DataKi:  82nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061879(8-Benzyl-3-[2,2-bis-(4-fluoro-phenyl)-ethyl]-8-aza...)
Affinity DataKi:  82.2nMAssay Description:Displacement of [3H]WIN-35428 from the dopamine transporter in rat caudate putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50061879(8-Benzyl-3-[2,2-bis-(4-fluoro-phenyl)-ethyl]-8-aza...)
Affinity DataKi:  132nMAssay Description:Binding affinity at human dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061879(8-Benzyl-3-[2,2-bis-(4-fluoro-phenyl)-ethyl]-8-aza...)
Affinity DataKi:  290nMAssay Description:In vitro inhibition of dopamine uptake in rat tissue, was determined using [3H]-DAU as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50061879(8-Benzyl-3-[2,2-bis-(4-fluoro-phenyl)-ethyl]-8-aza...)
Affinity DataKi:  640nMAssay Description:Binding affinity at human dopamine receptor D4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061879(8-Benzyl-3-[2,2-bis-(4-fluoro-phenyl)-ethyl]-8-aza...)
Affinity DataKi:  773nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M1 sites of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061879(8-Benzyl-3-[2,2-bis-(4-fluoro-phenyl)-ethyl]-8-aza...)
Affinity DataKi:  1.03E+3nMAssay Description:Compound is tested for displacement of [3H]pirenzepine at Metabotropic glutamate receptor 1 in Rat brain homogenate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061879(8-Benzyl-3-[2,2-bis-(4-fluoro-phenyl)-ethyl]-8-aza...)
Affinity DataKi:  2.08E+3nMAssay Description:Compound was evaluated for binding to Norepinephrine Transporter (NET) using [3H]-desmethylimipramine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed