BDBM50062663 2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic acid (2,6-dichloro-pyrimidin-4-yl)-amide::CHEMBL336099

SMILES FC(F)(F)c1nc(Cl)ncc1C(=O)Nc1cc(Cl)nc(Cl)n1

InChI Key InChIKey=VJBLSDVEUIUMEE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50062663   

TargetCyclic AMP-dependent transcription factor ATF-1(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062663(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062663(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibitory activity against human Jurkat T-Cells stably transfected with an Nuclear factor kappa B transcription factorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed