BDBM50063913 (R)-N*1*-((S)-Cyclohexyl-methylcarbamoyl-methyl)-N*4*-hydroxy-2-isobutyl-succinamide::CHEMBL281371

SMILES CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)CC(=O)NO)C1CCCCC1

InChI Key InChIKey=YOZKFIDLBXLPFF-HIFRSBDPSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50063913   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063913((R)-N*1*-((S)-Cyclohexyl-methylcarbamoyl-methyl)-N...)
Affinity DataIC50:  5nMAssay Description:Activity against Matrix metalloproteinase-9 (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063913((R)-N*1*-((S)-Cyclohexyl-methylcarbamoyl-methyl)-N...)
Affinity DataIC50:  2.30nMAssay Description:Activity against deletion mutant of MT1-MMP lacking the transmembrane domain (deltaMT1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063913((R)-N*1*-((S)-Cyclohexyl-methylcarbamoyl-methyl)-N...)
Affinity DataIC50:  8.40nMAssay Description:Activity against Matrix metalloproteinase-2 (MMP-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063913((R)-N*1*-((S)-Cyclohexyl-methylcarbamoyl-methyl)-N...)
Affinity DataIC50:  2.30nMAssay Description:Activity against Matrix metalloproteinase-3 (MMP-3).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Kanebo

Curated by ChEMBL
LigandPNGBDBM50063913((R)-N*1*-((S)-Cyclohexyl-methylcarbamoyl-methyl)-N...)
Affinity DataIC50:  5.40nMAssay Description:Activity against Matrix metalloproteinase-1 (MMP-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed