BDBM50064424 4-Iodo-2,6-diisopropyl-phenol::4-Iodo-2,6-diisopropylphenol::CHEMBL53267

SMILES CC(C)c1cc(I)cc(C(C)C)c1O

InChI Key InChIKey=JMJHJCFWTNRPEI-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50064424   

TargetGABA A receptor alpha-1/beta-1/gamma-2(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50064424(4-Iodo-2,6-diisopropyl-phenol | 4-Iodo-2,6-diisopr...)
Affinity DataEC50:  1.20E+4nMAssay Description:Modulation of GABA-induced chloride currents in Xenopus laevis oocytes expressing human alpha-1beta1-gamma2 GABA-A receptor subunitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Chicago Medical Center

Curated by ChEMBL
LigandPNGBDBM50064424(4-Iodo-2,6-diisopropyl-phenol | 4-Iodo-2,6-diisopr...)
Affinity DataEC50:  3.16E+4nMAssay Description:Direct activation of human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Chicago Medical Center

Curated by ChEMBL
LigandPNGBDBM50064424(4-Iodo-2,6-diisopropyl-phenol | 4-Iodo-2,6-diisopr...)
Affinity DataEC50:  1.00E+4nMAssay Description:Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA A receptor alpha-1/beta-1/gamma-2(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50064424(4-Iodo-2,6-diisopropyl-phenol | 4-Iodo-2,6-diisopr...)
Affinity DataEC50:  5.10E+4nMAssay Description:Direct activation of chloride current in Xenopus laevis oocytes expressing human alpha-1beta1-gamma2 GABA-A receptor subunitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed