BDBM50066659 1,3-BIS-(4-METHOXY-BENZENESULFONYL)-5,5-DIMETHYL-HEXAHYDRO-PYRIMIDINE-2-CARBOXYLIC ACID HYDROXYAMIDE::CHEMBL115727::MMP inhibitor II
SMILES COc1ccc(cc1)S(=O)(=O)N1CC(C)(C)CN(C1C(=O)NO)S(=O)(=O)c1ccc(OC)cc1
InChI Key InChIKey=MCSWSPNUKWMZHM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50066659
Affinity DataKi: 18nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3).Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 28.6nMAssay Description:Inhibition of human recombinant MMP3 catalytic domain incubated for 20 mins by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of truncated human recombinant MMP3 catalytic domain expressed in Escherichia coli BL21(DE3) after 3 hrs in presence of [H]-transferrinMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair