BDBM50068224 (E)-1,3-Bis-(4-hydroxy-phenyl)-propenone::1,3-bis(4-hydroxyphenyl)prop-2-en-1-one::4',4-Dihydroxychalcone::4,4'-dihydroxychalcone::CHEMBL145927

SMILES Oc1ccc(\C=C\C(=O)c2ccc(O)cc2)cc1

InChI Key InChIKey=FZQLEXXZAVVCCA-XCVCLJGOSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50068224   

TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Department Of Functional Crop

Curated by ChEMBL
LigandPNGBDBM50068224((E)-1,3-Bis-(4-hydroxy-phenyl)-propenone | 1,3-bis...)
Affinity DataKi:  2.90E+3nMAssay Description:Competitive inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue factor(Homo sapiens (Human))TBA
LigandPNGBDBM50068224((E)-1,3-Bis-(4-hydroxy-phenyl)-propenone | 1,3-bis...)
Affinity DataIC50:  0.960nMAssay Description:Inhibition of tissue factor in Homo sapiens (human) THP1-cells using factor 10a chromogenic substrate assessed as inhibition of LPS-iduced procoagula...More data for this Ligand-Target Pair
In DepthDetails Article
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50068224((E)-1,3-Bis-(4-hydroxy-phenyl)-propenone | 1,3-bis...)
Affinity DataIC50:  1.17E+5nMAssay Description:Inhibition of bovine milk xanthine oxidase pre-incubated for 30 mins followed by xanthine addition and measured every 30 secs for 5 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Department Of Functional Crop

Curated by ChEMBL
LigandPNGBDBM50068224((E)-1,3-Bis-(4-hydroxy-phenyl)-propenone | 1,3-bis...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed