BDBM50071216 2-[4-(3-Thiophen-3-yl-benzyl)-piperazin-1-yl]-pyrimidine::CHEMBL64597

SMILES C(N1CCN(CC1)c1ncccn1)c1cccc(c1)-c1ccsc1

InChI Key InChIKey=RRLCBKCJYXFQHA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50071216   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Darmstadt

Curated by ChEMBL
LigandPNGBDBM50071216(2-[4-(3-Thiophen-3-yl-benzyl)-piperazin-1-yl]-pyri...)
Affinity DataIC50:  3nMAssay Description:Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Darmstadt

Curated by ChEMBL
LigandPNGBDBM50071216(2-[4-(3-Thiophen-3-yl-benzyl)-piperazin-1-yl]-pyri...)
Affinity DataIC50:  600nMAssay Description:Binding affinity to 5-HT1A receptor in rat hippocampus by [3H]8-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Darmstadt

Curated by ChEMBL
LigandPNGBDBM50071216(2-[4-(3-Thiophen-3-yl-benzyl)-piperazin-1-yl]-pyri...)
Affinity DataIC50:  3nMAssay Description:Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Darmstadt

Curated by ChEMBL
LigandPNGBDBM50071216(2-[4-(3-Thiophen-3-yl-benzyl)-piperazin-1-yl]-pyri...)
Affinity DataIC50:  200nMAssay Description:Binding affinity to cloned human Dopamine receptor D3 expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Darmstadt

Curated by ChEMBL
LigandPNGBDBM50071216(2-[4-(3-Thiophen-3-yl-benzyl)-piperazin-1-yl]-pyri...)
Affinity DataIC50:  300nMAssay Description:Binding affinity to cloned human Dopamine receptor D2 expressed in A9L cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed