BDBM50072081 CHEMBL3407922
SMILES OC(=O)c1cc(ncn1)-c1ccc(OC2CC2)c(Cl)c1
InChI Key InChIKey=UPKQDTLLVVTZQT-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50072081
Affinity DataIC50: 5.10nMAssay Description:Inhibition of mouse KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of rat KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibition of KMO in human PBMCMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Ability to inhibit U-46,619-induced contraction of isolated strips of rabbit thoracic aorta, which is the measure of thromboxane receptor antagonismMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human KMO assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human KMO transfected in CHO cells assessed as conversion of kynurenine to 3-hydroxykynurenine by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human KMOMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of KMO in rat microglia cellsMore data for this Ligand-Target Pair