BDBM50072720 9-Fluoro-2,2,4-trimethyl-5-propylsulfanyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL325213

SMILES CCCSC1Oc2ccc(F)cc2-c2ccc3NC(C)(C)C=C(C)c3c12

InChI Key InChIKey=GKVFDSTWCKBSBV-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072720   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072720(9-Fluoro-2,2,4-trimethyl-5-propylsulfanyl-2,5-dihy...)
Affinity DataKi:  6.60nMAssay Description:Antagonist activity against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072720(9-Fluoro-2,2,4-trimethyl-5-propylsulfanyl-2,5-dihy...)
Affinity DataEC50:  12nMAssay Description:Agonist activity was determined against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072720(9-Fluoro-2,2,4-trimethyl-5-propylsulfanyl-2,5-dihy...)
Affinity DataEC50:  345nMAssay Description:Antagonist activity against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed