BDBM50074171 (S)-4-(3-{2-[(S)-3-(Benzylamino-methyl)-pyrrolidin-1-yl]-ethyl}-1H-indol-5-ylmethyl)-oxazolidin-2-one::CHEMBL159483

SMILES O=C1N[C@@H](Cc2ccc3[nH]cc(CCN4CC[C@@H](CNCc5ccccc5)C4)c3c2)CO1

InChI Key InChIKey=DZFRWAZJFQMVAM-GMAHTHKFSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50074171   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074171((S)-4-(3-{2-[(S)-3-(Benzylamino-methyl)-pyrrolidin...)
Affinity DataIC50:  17nMAssay Description:Affinity of compound towards 5-hydroxytryptamine 1A receptor was evaluated using radioligand binding techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074171((S)-4-(3-{2-[(S)-3-(Benzylamino-methyl)-pyrrolidin...)
Affinity DataEC50:  1.70nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074171((S)-4-(3-{2-[(S)-3-(Benzylamino-methyl)-pyrrolidin...)
Affinity DataIC50:  49nMAssay Description:Affinity of compound towards 5-hydroxytryptamine 1B receptor was evaluated using radioligand binding techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074171((S)-4-(3-{2-[(S)-3-(Benzylamino-methyl)-pyrrolidin...)
Affinity DataIC50:  3.00E+3nMAssay Description:Affinity of compound towards human 5-hydroxytryptamine 2A receptor was evaluated using radioligand binding techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074171((S)-4-(3-{2-[(S)-3-(Benzylamino-methyl)-pyrrolidin...)
Affinity DataIC50:  49nMAssay Description:Displacement of [3H]-5-HT binding from the cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074171((S)-4-(3-{2-[(S)-3-(Benzylamino-methyl)-pyrrolidin...)
Affinity DataIC50:  0.350nMAssay Description:Affinity of compound towards 5-hydroxytryptamine 1D receptor was evaluated using radioligand binding techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50074171((S)-4-(3-{2-[(S)-3-(Benzylamino-methyl)-pyrrolidin...)
Affinity DataIC50:  0.350nMAssay Description:Displacement of [3H]-5-HT binding from the cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed