BDBM50074978 2-[3-(4-Amino-butyl)-ureido]-N-[4-chloro-2-cyano-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-N-methyl-acetamide::CHEMBL113169

SMILES CN(C(=O)CNC(=O)NCCCCN)c1ccc(Cl)c(COc2cccc3ccc(C)nc23)c1C#N

InChI Key InChIKey=ISROIASQKHGIJZ-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074978   

TargetB2 bradykinin receptor(Cavia porcellus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50074978(2-[3-(4-Amino-butyl)-ureido]-N-[4-chloro-2-cyano-3...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of BK-induced (4x10E-8M) contraction of isolated guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Cavia porcellus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50074978(2-[3-(4-Amino-butyl)-ureido]-N-[4-chloro-2-cyano-3...)
Affinity DataEC50:  350nMAssay Description:Inhibition of specific binding of [3H]-BK to bradykinin B2 receptors of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Cavia porcellus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50074978(2-[3-(4-Amino-butyl)-ureido]-N-[4-chloro-2-cyano-3...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of specific binding of [3H]-BK to bradykinin B2 receptors of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed